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Sachiko Matsuzaki

Effects of matrix stiffness on epithelial to mesenchymal transition-like processes of endometrial epithelial cells :
Implications for the pathogenesis of endometriosis. Sci Rep. 2017


Effects of U0126 and MK2206 on cell growth and re-growth of endometriotic stromal cells grown on substrates of varying stiffness.
Sci Rep. 2017 Feb 20;7:42939.


Soft matrices inhibit cell proliferation and inactivate the fibrotic phenotype of deep endometriotic stromal cells in vitro.
Hum Reprod. 2016 Mar;31(3):541-53.


Impact of intraperitoneal pressure of a CO2 pneumoperitoneum on the surgical peritoneal environment. Hum Reprod. 2012 Jun;27(6):1613-23.


Impact of intraperitoneal pressure and duration of surgery on levels of tissue plasminogen activator and plasminogen activator inhibitor-1 mRNA in peritoneal tissues during laparoscopic surgery. Hum Reprod. 2011 May;26(5):1073-81.


Peritoneal tissue-oxygen tension during a carbon dioxide pneumoperitoneum in a mouse laparoscopic model with controlled respiratory support. Hum Reprod. 2007 Apr;22(4):1149-55. 

The Clermont Ferrand Endoscopic Group

30 years of Innovations in Endoscopic Surgery

The Founding Fathers of our group


From the first conservative laparoscopic treament of Ectopic pregnancy in 1974 by Hubert Manhes

To the first CO2 laser laparoscope in 1979

Bruhat M., Mage G., Manhes M. - Use of the CO2 laser via laparoscopy. In Laser Surgery III. Proceedings from the Third International Society forLaser Surgery, edited by I. Kaplan. Tel Aviv, International Society for Laser Surgery, 1979, 275.

Maurice Antoine BRUHAT

The Second Generation

Gérard MAGE
Jean-Luc POULY
Michel CANIS
up to 2003

The first Laparoscopic Radical Hysterectomy for cervical cancer on the 15 th of November 1989


Laparoscopic Hysterectomy with An effective uterine cannulation

The reverse technique

 for deep infiltrating endometriosis

Prolapse Surgery

The concept of a therapeutic 

Laparoscopic Peritoneal environment

Basic Research in endometriosis and peritoneal surgical environment

The present and the future ….

R. Botchorishvili
B. Rabischong
N. Bourdel
S. Campagne
C. Houlle
A.S. Gremeau

The First report on intra operative augmented reality on a mobile organ during a laparoscopic myomectomy.  

« Ten steps approach » in teaching oncologic surgery

« Ten steps approach » in teaching oncologic surgery

To a randomized study on the clinical and peritoneal molecular consequences of intraperitoneal pressure during prolapse surgery (submitted)

Fertility and sterility 2017 

Use of augmented reality in laparoscopic gynecology to visualize

« Ten steps approach » in teaching oncologic surgery

To the description of vaginal endoscopic surgical procedures 

The Clermont Ferrand Endoscopic Group

A teaching center founded in 1991

More than 500 students every year

  • The CICE is approved by the ESGE for the European certification

  • Resident and Fellow courses approved by the French college of Obstetrics and Gynecology

  • 4 diplomas in Gynecological Endosopy every year

  • Individual training with Access to the OR in Hopital Estaing 

  • Courses in Urology, Vascular surgery …

  • Training courses for OR nurses

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